The Newcombe square-and-add confidence interval for the difference

The Newcombe square-and-add confidence interval for the difference between paired probabilities.

Described in Chapter 8 "The Paired 2x2 Table"

Newcombe_square_and_add_CI_paired_2x2(n, alpha = 0.05)

Arguments

n

the observed table (a 2x2 matrix)

alpha

the nominal level, e.g. 0.05 for 95# CIs

Value

An object of the contingencytables_result class, basically a subclass of base::list(). Use the utils::str() function to see the specific elements returned.

Examples

# Airway hyper-responsiveness before and after stem cell transplantation
# (Bentur et al., 2009)
Newcombe_square_and_add_CI_paired_2x2(bentur_2009)
#> The Newcombe square-and-add CI: estimate = -0.2857 (95% CI -0.5069 to -0.0256)

# Complete response before and after consolidation therapy
# (Cavo et al., 2012)
Newcombe_square_and_add_CI_paired_2x2(cavo_2012)
#> The Newcombe square-and-add CI: estimate = -0.0621 (95% CI -0.1186 to -0.0046)